Title | CopyRighter: a rapid tool for improving the accuracy of microbial community profiles through lineage-specific gene copy number correction. |
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Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Angly FE, Dennis PG, Skarshewski A, Vanwonterghem I, Hugenholtz P, Tyson GW |
Journal | Microbiome |
Volume | 2 |
Pagination | 11 |
Date Published | 2014 Apr 7 |
ISSN | 2049-2618 |
Abstract | Culture-independent molecular surveys targeting conserved marker genes, most notably 16S rRNA, to assess microbial diversity remain semi-quantitative due to variations in the number of gene copies between species. |
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