TitleGroopM: an automated tool for the recovery of population genomes from related metagenomes.
Publication TypeJournal Article
Year of Publication2014
AuthorsImelfort M, Parks DH, Woodcroft B.J., Dennis P, Hugenholtz P, Tyson GW
JournalPeerJ
Volume2
Paginatione603
Date Published2014
ISSN2167-8359
AbstractMetagenomic binning methods that leverage differential population abundances in microbial communities (differential coverage) are emerging as a complementary approach to conventional composition-based binning. Here we introduce GroopM, an automated binning tool that primarily uses differential coverage to obtain high fidelity population genomes from related metagenomes. We demonstrate the effectiveness of GroopM using synthetic and real-world metagenomes, and show that GroopM produces results comparable with more time consuming, labor-intensive methods.
DOI10.7717/peerj.603

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