GroopM: an automated tool for the recovery of population genomes from related metagenomes.

Title	GroopM: an automated tool for the recovery of population genomes from related metagenomes.
Publication Type	Journal Article
Year of Publication	2014
Authors	Imelfort M, Parks DH, Woodcroft B.J., Dennis P, Hugenholtz P, Tyson GW
Journal	PeerJ
Volume	2
Pagination	e603
Date Published	2014
ISSN	2167-8359
Abstract	Metagenomic binning methods that leverage differential population abundances in microbial communities (differential coverage) are emerging as a complementary approach to conventional composition-based binning. Here we introduce GroopM, an automated binning tool that primarily uses differential coverage to obtain high fidelity population genomes from related metagenomes. We demonstrate the effectiveness of GroopM using synthetic and real-world metagenomes, and show that GroopM produces results comparable with more time consuming, labor-intensive methods.
DOI	10.7717/peerj.603

Search form